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王轶英
2019-05-10 15:24     (阅读:)

1.个人信息

  女,博士,主任医师,教授,邮箱:wangyiying1008@126.com

2.受教育经历

  2003.9–2006.6, 华中科技大学同济医学院, 妇产科学, 博士, 导师: 邹丽

  2000.9–2003.7, 华中科技大学同济医学院, 妇产科学, 硕士, 导师: 邹丽

  1990.9–1995.7, 河南医科大学, 儿科医学, 学士, 导师:

3.工作经历

  2012.7-2013.9, 美国亚利桑那医学中心, 妇产科系 病理系, 访问学者

  2006.6-至今, 河南大学, 河南省人民医院, 主任医师

  1995.8-2000.8, 河南大学, 第一附属医院, 主治医师

4.研究兴趣

  妇科肿瘤的分子机制;妇科肿瘤早期诊断、预防;妇科肿瘤免疫及靶向治疗;母胎医学

5.承担项目情况(一般为近5年内的)

  1)中国lynch综合征相关子宫内膜癌的发病情况及防治策略(162102410040)2016河南省科技厅科技攻关计划 20.0万

  2)IMP3在早期浆液性卵巢癌癌变过程中的预测作用(2015河南卫计委项目)1.5万201503168

  3)2015年 5451项目妇科恶性肿瘤早期诊治及多学科综合治疗 卫生厅 16万

  4)2016年 河南省人民医院23456工程,50万/年

  5)2018年 河南省自然基金项目ZC20180062  输卵管分泌细胞扩增在卵巢浆液性癌发生的分子机制及其早期检测和预防价值 河南省科技厅 20万

6.代表性论著

  论文

  中华核心论文:

  1井佳雨,牟婧祎,王轶英,李雅丽,王悦,宫颈癌及癌前病变筛查方法研究进展, 中华实用诊断与治疗杂志,2017,31(2):203-205.

  2赵瑞皎,王轶英,李真,吴凯彦,孔令非,郑文新. 盆腔高级别浆液性癌中输卵管伞端上皮病变的病理学特征, [J].中华病理学杂志,2017,46(8:542-547.)

  3王轶英,王悦,孔北华,Wenxin Zheng. 人乳头瘤状病毒定量检测的临床意义与研究进展, [J]. 中华妇产科杂志2017, 52(8):569-572.

  4王轶英,王悦,乔友林,孔北华,Wenxin Zheng 中国宫颈癌筛查未来之路---细胞学初筛的弃或守?[J]. 中国实用妇科与产科杂志, 2017, 33(3):212-214.

  5 魏利, 吴凯彦, 王轶英. 卵巢子宫内膜异位症的输卵管起源及其临床意义[J]. 实用妇产科杂志, 2015, 31(11).

  SCI收录论文:

  Wang Y, Hong S, Mu J, Wang Y, Lea L, Kong B, Zheng W. Tubal Origin of (Ovarian) Low-Grade Serous Carcinoma:A Gene Expression Profile Study. J Oncology. 2019

  Wang Y, Chen H, Zhao M, Fadare O, Zheng W. Primary Ovarian Pregnancy: A Case Series and Analysis. Int J Gynecol Pathol. 2019 Jan;38(1):85-91.

  Li YJ, Wang Y, Wang Y. MicroRNA‐99bsuppresseshumancervicalcancercellactivity by inhibiting the PI3K/AKT/mTOR signaling pathway. J Cell Physiol. 2019 Jun;234(6):9577-9591.

  Yang L, Lv Q , Chen W, Sun J, Wu Y, Wang Y, Chen X, Chen X, Zhang Z. Presence of embryonic DNA in culture medium. Oncotaget.2017 Jun 29;8(40):67805-67809.

  Chen H, Klein R, Arnold S, Wang Y, Chambers S, Zheng W. Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection. J Vis Exp. 2017 Jul 25;(125).

  Wang Y, Wang Y, Wei L, Hong S, Zhao M, Zhang X, Zheng W*. BRCA1 expression, proliferative and apoptotic activities in ovarian epithelial inclusions. J Ovarian Res. 2017;10 (1): 12. doi: 10.1186/s13048-017-0307-6. PMID: 28270171

  Fan R, Wang Y, Wang Y, Wei L, Zheng W. Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-survivin pathway. Am J Transl Res. 2017 Mar 15;9(3):1483-1491.

  Li L, Wang X, Park JY, Chen H, Wang Y, Zheng W. Pathological Findings of Explanted Vaginal Mesh. Human Pathology, 2017 Nov;69:46-54.

  Wang Y, Wang Y, Zhang Z*, Park JY, Guo D, Liao H, Yi X, Zheng Y, Zhang D, Chambers SK, Zheng W*.Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-AKR1C1 pathway,Oncotarget,2016,7(9):10363-10372

  Wang Y, Li L, Wang Y, Tang SN, Zheng W*. Fallopian tube secretory cell expansion: a sensitive biomarker for ovarian serous carcinogenesis, Am J Transl Res,2015 Oct 15;7(10):2082-90

  Wang Y, Mang M, Wang Y, Wang L, Klein R, Kong B, Zheng W*. Tubal origin of ovarian endometriosis and clear cell and endometrioid carcinoma, Am J Cancer Res,2015 Feb 15;5(3):869-79

  Wang Y, Wang Y, Li D, Li L, Zhang W, Yao G, Jiang Z, Zheng W*. IMP3 signatures of fallopian tube: a risk for pelvic serous cancers,J Hematol Oncol,2014, 7(1) :49

  Wang Y, Li L, Wang Y, Yuan Z, Zhang W, Hatch KD, Zheng W*. IMP3 as a cytoplasmic biomarker for early serous tubal carcinogenesis, J Exp Clin Cancer Res,2014, 33(1): 60

  Wang Y, Wang Y, Zheng W*.Cytologic changes of ovarian epithelial cancer induced by neoadjuvant chemotherapy,Int J Clin Exp Pathol, 2013 Sep 15;6(10):2121-8

  Wang Y, Wang Y, Ning Y, Kong B, Zheng W. Lynch syndrome related endometrial cacer: aspects and concerns, Progress in Obstetrics & Gynecology, 2013(7):523-526

  Wang Y#, Wang Y#, Li J, Yuan Z, Yuan B, Zhang T, Cragun JM, Kong B, Zheng W*. PAX8: a sensitive and specific marker to identify cancer cells of ovarian origin for patients prior to neoadjuvant chemotherapy, J Hematol Oncol,2013 Aug 19;6:60

  Wang Y#, Wang Y#, Li J, Cragun J, Hatch K, Chambers SK, Zheng W*.Lynch syndrome related endometrial cancer: clinical significance beyond the endometrium, J Hematol Oncol, 2013 Mar 25;6:22

  Jia L, Yuan Z, Wang Y, Cragun JM, Kong B, Zheng W. Primary sources of pelvic serous cancer in patients with endometrial intraepithelial carcinoma, Mod Pathol,2014 Jun,13

  Yuan Z, Wang L, Wang Y, Zhang T, Li L, Cragun JM, Chambers SK, Kong B, Zheng W. Tubal origin of ovarian endometriosis. Mod Pathol,2014 Jan,3

  Yuan Z, Wang Y, Cragun JM, Chambers SK, Zheng W: Cell origin of endometriosis: contribution by the fallopian tube epithelium. Am J Clin Exp Obstet Gynecol,2013,1:37-42

  Han LM, Wei L, Ferguson DC, Chambers SK, Fadare O, Wang Y, Zheng W.From endometrial glandular dysplasia to endometrial serous carcinoma: insights into underlying biological aspects, Am J Clin Exp Obstet Gynecol,2013,1(1):1-16

  Li J, Ning Y, Abushahin N, Yuan Z, Wang Y, Wang Y, Yuan B, Cragun JM, Chambers SK, Hatch K, Kong B, Zheng W. Secretory cell expansion with aging: risk for pelvic serous carcinogenesis,Gynecol Oncol,2013,Dec;131(3):555-60

  Ning Y, Wang Y, Wang Y, Zheng W. Lynch Syndrome related endometrial cancer: Current status and future perspectives,Clin J Pathol,2013,8,1-4.

7.奖励:科技成果

  1 卵巢高级别浆液性癌早期诊治的临床与基础研究

  2017河南省卫生厅 一等奖 第一名

  2 卵巢高级别浆液性癌早期诊治的临床应用

  2017河南省科技厅 二等奖 第一名

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