1.个人信息
医学博士、副教授、研究生导师、开封市科技创新人才。毕业于北京大学心血管研究所。熟悉相关通识科学、基础医学、临床医学知识，掌握分子生物学、生物信息学、医学统计学知识和技术，发表有多篇高水平研究论文。
现担任河南大学临床资源转化重点实验室负责人。主持多项国家和省级科研项目，科研经费充足，与国内多个顶尖科研机构和医院有良好的合作关系，能为研究生提供较好的科研条件。与多个临床科室建立有良好的科研合作，可与相应科室主任共同培养内科学专业的学术型和专业型研究生。
邮箱：asdncg@163.com
2.教育经历
2004.9—2009.7 河南大学 口腔医学 学士
2010.9—2015.7 北京大学 病理生理学 博士
3.工作经历
2015.7—现在，河南大学第一临床学院，河南大学临床资源转化重点实验室，负责人。
4.研究兴趣
a) 细胞外囊泡的生物学功能及临床应用;
b) 生物医学数据的深度分析与知识转化.
5.承担项目情况
（1）巨噬泡沫细胞微粒通过外源性microRNA调控血管平滑肌细胞表型转化的机制研究（81800395），2019-2021，国家自然科学基金青年项目，主持
（4）巨噬泡沫细胞所产生的微粒促进血管平滑肌细胞迁移和粘附（SBGJ2018061），2019-2021，河南省医学科技攻关省部共建项目，主持
（2）巨噬泡沫细胞来源的微粒在动脉粥样硬化病中的诊疗价值研究（182102310159），2018-2019，河南省科技发展计划项目，主持
（3）动脉粥样斑块中巨噬细胞来源微粒的作用及其机制（18A320018），2018-2019，河南省教育厅科学技术研究重点项目，主持
6.代表性论著
[1] *Niu C, Wang X, Zhao M, Cai T, Liu P, Li J, Willard B, Zu L, Zhou E, Li Y, Pan B, Yang F, Zheng L. Macrophage foam cell-derived extracellular vesicles promote vascular smooth muscle cell migration and adhesion. J Am Heart Assoc. 2016; 5(10).
[2] Zu, L, *Niu C, Li J, Shan L, Li L, Zhang D, Willard B, Zheng L. Proteomic research of high glucose-activated endothelial microparticles and related proteins to Alzheimer’s disease. Diab Vasc Dis Res. 2015; 12(6):467-70.
[3] Zu L, Ren C, Pan B, Zhou B, Zhou E, Niu C, Wang X, Zhao M, Gao W, Guo L, Zheng L. Endothelial microparticles after antihypertensive and lipid-lowering therapy inhibit the adhesion of monocytes to endothelial cells. Int J Cardiol. 2016; 202:756-9.
[4] Liu Y, Lv P, Jin H, Cui W, Niu C, Zhao M, Fan C, Teng Y, Pan B, Peng Q, Luo J, Zheng L, Huang Y. Association between Low Estimated Glomerular Filtration Rate and Risk of Cerebral Small-Vessel Diseases: A Meta-Analysis. J Stroke Cerebrovasc Dis. 2016;25(3):710-6.
[5] Huang L, Niu C, Willard B, Zhao W, Liu L, He W, Wu T, Yang S, Feng S, Mu Y, Zheng L, Li K. Proteomic analysis of porcine mesenchymal stem cells derived from bone marrow and umbilical cord: implication of the proteins involved in the higher migration capability of bone marrow mesenchymal stem cells. Stem Cell Res Ther. 2015;6(1):77.
[6] Shan L, Li J, Zu L, Niu C, Ferro A, Zhang Y, Zheng L, Ji Y. Platelet-derived microparticles are implicated in remote ischemia conditioning in a rat model of cerebral infarction. CNS Neurosci Ther. 2013;19(12):917-25.
[7] Li X, Gu F, Liu Z, Niu C, Wang Y, Li N, Pan B, He D, Kong J, Zhang S, Yao Y, Zheng L. VEGF111b, a C-terminal splice variant of VEGF-A and induced by mitomycin C, inhibits ovarian cancer growth. J Transl Med. 2015; 13:164.
[8] Shen H, Zhou E, Wei X, Fu Z, Niu C, Li Y, Pan B, Mathew AV, Wang X, Pennathur S, Zheng L, Wang Y. High density lipoprotein promotes proliferation of adipose-derived stem cells via S1P1 receptor and Akt, ERK1/2 signal pathways. Stem Cell Res Ther. 2015; 6:95.
[9] Tong X, Lv P, Mathew AV, Liu D, Niu C, Wang Y, Ji L, Li J, Fu Z, Pan B, Pennathur S, Zheng L, Huang Y. The compensatory enrichment of sphingosine -1- phosphate harbored on glycated high-density lipoprotein restores endothelial protective function in type 2 diabetes mellitus. Cardiovasc Diabetol. 2014; 13:82.
[10] Tong X, Peng H, Liu D, Ji L, Niu C, Ren J, Pan B, Hu J, Zheng L, Huang Y. High-density lipoprotein of patients with type 2 diabetes mellitus upregulates cyclooxgenase-2 expression and prostacyclin I-2 release in endothelial cells: relationship with HDL-associated sphingosine-1-phosphate. Cardiovasc Diabetol. 2013; 12:27.
[11] Pan B, Yu B, Ren H, Willard B, Pan L, Zu L, Shen X, Ma Y, Li X, Niu C, Kong J, Kang S, Eugene Chen Y, Pennathur S, Zheng L. High-density lipoprotein nitration and chlorination catalyzed by myeloperoxidase impair its effect of promoting endothelial repair. Free Radic Biol Med. 2013; 60:272-81.
[12] Pan B, Ren H, Lv X, Zhao Y, Yu B, He Y, Ma Y, Niu C, Kong J, Yu F, Sun WB, Zhang Y, Willard B, Zheng L. Hypochlorite-induced oxidative stress elevates the capability of HDL in promoting breast cancer metastasis. J Transl Med. 2012; 10:65.
[13] Pan B, Ren H, He Y, Lv X, Ma Y, Li J, Huang L, Yu B, Kong J, Niu C, Zhang Y, Sun WB, Zheng L. HDL of patients with type 2 diabetes mellitus elevates the capability of promoting breast cancer metastasis. Clin Cancer Res. 2012;18(5):1246-56.
